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Jonathan’s genome reveals aging and cancer-linked gene variants

By Drooid · · How we work

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Story summary
  • Scientists on Saint Helena sequenced the genome of Jonathan, a 194-year-old Aldabra giant tortoise.
  • The genome contained 287 unique variants linked to DNA repair, tumor suppression and mitochondrial function.
  • Jonathan’s mitochondrial gene regions showed low methylation entropy, similar to a five-year-old tortoise.
  • Researchers identified extra copies of a gene that targets aging and cancer cells.
  • The study appeared in Science Advances on Oct 7 2026.