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ADHD Linked to 4.6-Fold Higher Dementia Risk

By Drooid · · How we work

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ADHD Linked to Dementia
  • University of Pittsburgh researchers found adults with ADHD have over fourfold higher dementia risk.
  • The analysis used electronic health records of more than 187,000 U.S. adults aged 50 or older.
  • Cognitive impairment affected 6.7% of participants with ADHD versus 3.4% without.
  • Adjusted models showed ADHD associated with a 4.6-fold higher hazard of cognitive impairment (HR = 4.60, P < .001).
  • The highest ADHD polygenic risk quintile faced a 35% greater hazard of dementia (HR = 1.35).
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