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Joe Manganiello Details 2016 Surgery, Autoimmune Illness in Memoir

By Drooid · Oct 14, 2026, 3:14 AM UTC · How we work

Summary

Story summary

Joe Manganiello revealed his seven-year autoimmune illness and emergency intestinal surgery in the memoir Bloodlines.
Doctors removed his entire large intestine in 2016, leaving him with an ostomy bag.
He lost 60 pounds in two weeks after the surgery.
He was unable to walk and his eye became cross-eyed post-operation.
A month after discharge, Manganiello received a call to play Deathstroke in Ben Affleck’s canceled Batman film.

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Story summary

Joe Manganiello revealed his seven-year autoimmune illness and emergency intestinal surgery in the memoir Bloodlines.
Doctors removed his entire large intestine in 2016, leaving him with an ostomy bag.
He lost 60 pounds in two weeks after the surgery.
He was unable to walk and his eye became cross-eyed post-operation.
A month after discharge, Manganiello received a call to play Deathstroke in Ben Affleck’s canceled Batman film.