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Microsoft’s AI Diagnostic Orchestrator Beats Doctors on NEJM Cases

By Drooid · Oct 23, 2026, 6:20 AM UTC · How we work

Summary

Story summary

Microsoft’s U.S. AI team unveiled the Diagnostic Orchestrator, which outperformed physicians on complex cases.
The Orchestrator achieved 83.2% accuracy on NEJM cases, versus 36.1% for doctors using references.
Without references, doctors scored about 22%, making the AI roughly four times more accurate.
Researchers said AI work-ups cost less than doctor-ordered ones, based on simulated savings.
Microsoft will open-source its benchmark SDBench and begin testing at Beth Israel Deaconess Medical Center.

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Story summary

Microsoft’s U.S. AI team unveiled the Diagnostic Orchestrator, which outperformed physicians on complex cases.
The Orchestrator achieved 83.2% accuracy on NEJM cases, versus 36.1% for doctors using references.
Without references, doctors scored about 22%, making the AI roughly four times more accurate.
Researchers said AI work-ups cost less than doctor-ordered ones, based on simulated savings.
Microsoft will open-source its benchmark SDBench and begin testing at Beth Israel Deaconess Medical Center.