Back to today’s briefing

Story perspectives

Mirtazapine Triumphs Over Amitriptyline for Insomnia Relief

1/22/2025

25 6

Summary

Story summary

In a groundbreaking study from the Netherlands, researchers examined the effects of low-dose mirtazapine and amitriptyline on insomnia in 80 patients. Mirtazapine emerged as a champion, significantly alleviating insomnia symptoms within six weeks, while amitriptyline's impact was minimal. Experts caution against prolonged use, suggesting mirtazapine is best reserved for short-term relief.

1 of 1

Story summary

In a groundbreaking study from the Netherlands, researchers examined the effects of low-dose mirtazapine and amitriptyline on insomnia in 80 patients. Mirtazapine emerged as a champion, significantly alleviating insomnia symptoms within six weeks, while amitriptyline's impact was minimal. Experts caution against prolonged use, suggesting mirtazapine is best reserved for short-term relief.