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New AI Model Simulates Evolution, Creates Game-Changing Protein

1/28/2025

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Summary

Story summary

In a groundbreaking study, researchers at EvolutionaryScale unveiled ESM3, an AI model that simulated 500 million years of evolution to engineer a revolutionary green fluorescent protein, esmGFP. With a striking 58% similarity to its natural counterpart, this innovation holds promise for drug design and tackling environmental challenges like plastic waste. The findings are featured in the journal Science.

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Story summary

In a groundbreaking study, researchers at EvolutionaryScale unveiled ESM3, an AI model that simulated 500 million years of evolution to engineer a revolutionary green fluorescent protein, esmGFP. With a striking 58% similarity to its natural counterpart, this innovation holds promise for drug design and tackling environmental challenges like plastic waste. The findings are featured in the journal Science.