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Key Transporters Unveiled for Boosting Energy Health

2/2/2025

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Summary

Story summary

Researchers have uncovered that the equilibrative nucleoside transporters ENT1 and ENT2 are essential for the uptake of nicotinamide (NAM) in human cells. This breakthrough sheds light on their significant role in maintaining NAD+ levels, which are crucial for energy production. Boosting NAM transport could pave the way for innovative treatments for metabolic disorders and age-related health issues.

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Story summary

Researchers have uncovered that the equilibrative nucleoside transporters ENT1 and ENT2 are essential for the uptake of nicotinamide (NAM) in human cells. This breakthrough sheds light on their significant role in maintaining NAD+ levels, which are crucial for energy production. Boosting NAM transport could pave the way for innovative treatments for metabolic disorders and age-related health issues.